Drug Interactions of Niacin:
© Niacin is used to treat high cholesterol and
Pellagra.
© Mechanism of Action of Niacin:
© Niacin can interact majorly with Statins (Simvastatin,
Rosuvastatin, Atorvastatin, Lovastatin, etc) and moderately with Warfarin.
© If coadministration of Niacin and Statins
is required, monitor the patient for signs and symptoms of myopathy or
rhabdomyolysis (Muscle pain, Tenderness, or weakness). Periodic creatine kinase
(CK) determinations may be advisable.
© More frequent monitoring of INR and/or
prothrombin time is recommended, if concomitant therapy is required.
© The occurrence of significant morbidity and
mortality can be reduced by minimizing the risk for drug interactions.
© The hyperlipidemic patients should bring a list
of all the drugs they are taking including prescription drugs, over-the-counter
drugs, and any supplements, herbal or otherwise, during their visit to the Doctor
or Pharmacist.
© The risk of adverse effects could be reduced
and the quality of life for patients improved by healthcare professionals
through the screening, education, and follow up on suspected drug interactions.
© If possible, the hyperlipidemic patients are
recommended to fill all their prescriptions at one pharmacy.
