Friday, 10 July 2020

Drug Interactions of Thiazide Diuretics:





     ·       Thiazide diuretics include
Ø Chlorothiazide
Ø Hydrochlorothiazide
     ·       Thiazide-like diuretics include
Ø Indapamide
Ø Chlorthalidone
     ·       Thiazide diuretics are primarily prescribed in the management of hypertension and edema associated with chronic heart failure, renal dysfunction, and hepatic cirrhosis. Besides, these drugs are also used to treat high blood pressure induced by corticosteroids and estrogen.
     ·       Drug interaction resulting from Thiazide-induced hypokalemia
Ø Digoxin
     ·       Drug interaction resulting from Thiazide-induced hyponatremia
Ø Flecaininde
     ·       Drug interaction resulting from Thiazide-induced hypovolemia
Ø Dofetilide
     ·       Pharmacological interaction of Thiazide diuretics
Ø Lithium
Ø ACE inhibitors
Ø NSAIDs
Ø Antidiabetics
Ø  Vitamin D
Ø Herbs (Licorice and Ginkgo)
     ·       The prescribers and the pharmacists are required to be aware of the drug interactions of thiazide diuretics.




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Drug Interactions of Thiazide Diuretics:

https://www.researchgate.net/publication/342864519_Pharmacodynamic_interactions_of_thiazide_diuretics http://www.ijmdc.com/?mno=51031...