Drug Interactions of Hirudins:
© Hirudins include Bivalirudin, Desirudin and
Lepirudin.
© Drugs increasing the risk of Hirudins associated
bleeding, include…
· Warfarin
· Heparin
· Enoxaparin
· Dalteparin
· Tinzaparin
· Fondaparinux
· Phenindione
· Argatroban
· Rivaroxaban
· Apixaban
· Dabigatran
© Drug interactions can result in significant morbidity and mortality
and thus minimizing the risk for drug interactions should be a goal in drug
therapy.
© The patients with clotting disorders should bring a list of all of
the drugs they are taking including prescription drugs, over-the-counter drugs,
and any supplements, herbal or otherwise, during their visit to the doctor or
pharmacist.
© The risk of adverse effects could be reduced by healthcare
professionals through the screening, education, and follow up on suspected drug
interactions.
© If possible, the patients are recommended to fill all their
prescriptions at one pharmacy.
© Pharmacists can play a crucial role in identifying possible drug
interactions by asking patients on Anticoagulants about their herbal and other
alternative medicine product use.