Interactions of Insulin:
¢ The therapeutic efficacy of Insulin either increased or decreased by interacting with other drugs.
¢ Further reductions of blood glucose or exacerbation of hypoglycemia may be resulted due to the concomitant use of Insulin and drugs such as Fluoroquinolones, Anabolic steroids (nandrolone, methandienone, testosterone propionate or stanozolol), Antimalarials (Hydroxychloroquine, chloroquine), Orlistat, Bitter melon, Ginkgo, Ginseng, Gymnema extracts, Fenugreek and Alcohol.
¢ The blood sugar level may be elevated by the coadministration of Insulin and Antipsychotics.
¢ The therapeutic efficacy of Insulin is reduced in smokers due to decreased absorption.
¢ Betablockers may delay the recovery from hypoglycemia induced by Insulin.
¢ Thiazolidinediones (Pioglitazone or rosiglitazone) may potentiate the renal effects of insulin on sodium and water retention which may increase the incidence of heart failure.
¢ The diabetics are encouraged to ask their doctor or pharmacist to look over their medication list for any potentially dangerous combinations.
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