Sunday, 15 June 2014

Drug Interactions of Antidiabetics (Part 7):

Drug Interactions of Alpha-glucosidase inhibitors:

}  Acarbose, Miglitol and Voglibose are the antidiabetic drugs which prevent the digestion of carbohydrates by inhibiting Alpha-glucosidase enzymes found in the brush border of the small intestines.
}  Acarbose may decrease the therapeutic efficacy of Digoxin by reducing its absorption.
}  Acarbose may increase the risk of bleeding by increasing the absorption of Warfarin.
}  The risk of hypoglycemia may be elevated by the concomitant use of Acarbose and Sulfonylureas, Neomycin and Guar gum.
}  The drugs like Pancreatin, Amylase and Activated charcoal may reduce the effectiveness of acarbose.
}  The diabetics should bring a list of all of the drugs they are taking, including prescription drugs, over-the-counter drugs, and any supplements, herbal products, etc. during their visit to the doctor or pharmacist, to minimize the possibility of potentially dangerous combinations.

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Drug Interactions of Thiazide Diuretics:

https://www.researchgate.net/publication/342864519_Pharmacodynamic_interactions_of_thiazide_diuretics http://www.ijmdc.com/?mno=51031...