§
Glucagon-like
peptide-1 receptor agonists are incretin mimetics and they help to manage the
blood glucose of patients with type 2 diabetes mellitus.
§ The members of this class include Exenatide,
Liraglutide, Lixisenatide, Albiglutide, Dulaglutide and Semaglutide.
§
They are
administered subcutaneously to manage fasting and postprandial blood glucose.
§
GLP-1 receptor agonists may interact with
Ø Acetaminophen
Ø Digoxin
Ø Warfarin
Ø Oral contraceptive pills
Ø Metformin
Ø Statins
Ø Angiotensin Converting Enzyme Inhibitors
Ø Griseofulvin
§
The delay in absorption of interacting drugs could be avoided by
taking 1 hour before the administration of Glucagon-like peptide-1 receptor
agonists.
§ Healthcare professionals through the screening, education, and
follow up on suspected drug interactions could reduce the risk of adverse
effects.
§ The diabetic patients should always consult their physician and
pharmacist before taking any new medication.
§ The diabetic patients should bring a list of all of the drugs they
are taking (or simply bring the drugs themselves), including prescription
drugs, over-the-counter drugs, and any supplements, herbal or otherwise, during
their visit to the doctor or pharmacist.
§ The diabetic patients are encouraged to ask their doctor or
pharmacist to look over their list for any potentially dangerous combinations.
§ It is recommended that people fill all their prescriptions at one
pharmacy, if possible.
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