Drug Interactions of Alpha 1 Blockers:
© Alpha 1 blockers include Irreversible α1 blockers (Phenoxybenzamine), Reversible α1 blockers (Imidazoline derivative - Phentolamine (α1, α2 blocker)) and α1 Selective blockers (Quinazoline Derivative – Prazosin, Terazosin and Doxazosin).
© Alpha 1 blockers are used to treat various illnesses including Benign Prostatic Hyperplasia (BPH), Hypertension, etc.
© Alpha 1 blockers can interact majorly with drugs such as Phosphodiesterase 5 inhibitors (Sildenafil, Tadalafil) and Asenapine.
© Moderate interaction of Alpha 1 blockers includes Beta blockers and Yohimbine (Alpha 2 blocker).
© Use caution when PDE 5 inhibitors for erectile dysfunction (ED) and Alpha 1 blockers are coadministered.
© Monitor blood pressure and reduce the dosage of the Alpha 1 blockers when they are coadministered with Asenapine.
© Monitor the patient closely for hypotension while using Alpha 1 blocker and Beta blocker concomitantly.
© Avoid concomitant use of yohimbine and alpha-1 adrenergic blockers.
© The patients with hypertension should bring a list of all medications they are taking including prescription drugs, over the counter (OTC) drugs and any supplements during their visit to the doctor or pharmacist.
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