§ Pramlintide is an Amylin analogue and it helps to treat type 1 and type 2 diabetes mellitus.
§ Pramlintide decreases the postprandial glucose concentrations through at least three mechanisms including reduction of postprandial glucagon secretion, slowing of gastric emptying and suppression of appetite by a central mechanism.
§ No clinically significant drug interactions have been reported with the use of Pramlintide, though there are few possible interactions related to delayed absorption of oral medications.
§ Absorption Interactions
Ø Acetaminophen (Paracetamol)
Ø Oral contraceptives
Ø Antibiotics
§ Pharmaceutical Interactions
Ø Insulin
§ Healthcare professionals through the screening, education, and follow up on suspected drug interactions could reduce the risk of adverse effects.
§ The diabetic patients should always consult their physician and pharmacist before taking any new medication.
§ The diabetic patients should bring a list of all of the drugs they are taking (or simply bring the drugs themselves), including prescription drugs, over-the-counter drugs, and any supplements, herbal or otherwise, during their visit to the doctor or pharmacist.
§ They are encouraged to ask their doctor or pharmacist to look over their list for any potentially dangerous combinations.
§ It is recommended that people fill all their prescriptions at one pharmacy, if possible.
