§ Minerals are one of the common types of dietary supplements and some of them can interact with prescription or OTC medicines and decrease the therapeutic efficacy or increase the toxicity of medicines.
§ The macro minerals like Calcium, Potassium, Magnesium and micro minerals such as Chromium, Iron, Selenium and Zinc are involved in some drug interactions.
§ Calcium may reduce the absorption of certain Antibiotics (Tetracyclines and Fluoroquinolones), Levothyroxine and Bisphosphonates leading to reduced therapeutic efficacy.
§ The risk of hyperkalemia might be elevated by the concomitant use of Potassium supplements and other drugs such as ACEIs / ARBs, Potassium sparing Diuretics, Digoxin and Indomethacin.
§ Magnesium supplements can decrease the absorption of oral Bisphosphonates, Tetracyclines and Fluoroquinolones. Magnesium can increase the risk of muscle related side effects of Aminoglycosides and Muscle relaxants.
§ Concomitant use of Chromium and Insulin might increase the risk of hypoglycemia. Chromium may reduce the absorption of levothyroxine.
§ Iron supplements can decrease the absorption of Levodopa, oral Bisphosphonates, Fluoroquinolones and Tetracyclines.
§ Taking Selenium along with Anticoagulants or Antiplatelets might increase the chances of bruising and bleeding. The effectiveness of Statins and Niacin might be decreased by Selenium.
§ Zinc dietary supplements can reduce absorption of Tetracyclines, Fluoroquinolones and Penicillamine.
§ Consumers should consult with the doctor, pharmacist or dietitian to know about the safety of a supplement or herb.
§ Dietary supplements are not drugs and are not intended to treat, diagnose, mitigate, prevent, or cure diseases.
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