Drug Interactions of Glycoprotein
IIB/IIIA inhibitors:
More Presentations from Naina Mohamed, PhD
© Glycoprotein IIB/IIIA inhibitors
include Abciximab, Eptifibatide and
Tirofiban.
© They are intended to be administered by intravenous route only.
© They are frequently used during percutaneous coronary
intervention (PCI). They may also be used to treat acute coronary syndromes
(ACS).
© Mechanism of action of Glycoprotein IIB/IIIA inhibitors:
© Drugs increasing Glycoprotein IIB/IIIA inhibitors associated
bleeding include…
Ø Other Antiplatelets (Aspirin,
Ticlopidine, Dipyridamole, etc.)
Ø Ginkgo
© Drug interactions can result in significant morbidity and mortality
and thus minimizing the risk for drug interactions should be a goal in drug
therapy.
© The patients on antiplatelet therapy should bring a list of all of
the drugs they are taking including prescription drugs, over-the-counter drugs,
and any supplements, herbal or otherwise, during their visit to the doctor or
pharmacist.
© The risk of adverse effects could be reduced by healthcare
professionals through the screening, education, and follow up on suspected drug
interactions.
© If possible, the patients are recommended to fill all their
prescriptions at one pharmacy.
© Pharmacists can play a crucial role in identifying possible drug
interactions by asking patients about their herbal and other alternative
medicine product use.
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