Tuesday 19 September 2017

Drug Interactions of Antiplatelets (Part 4):


Drug Interactions of Glycoprotein IIB/IIIA inhibitors:



More Presentations from Naina Mohamed, PhD


©   Glycoprotein IIB/IIIA inhibitors include Abciximab, Eptifibatide and Tirofiban.

©   They are intended to be administered by intravenous route only.

©    They are frequently used during percutaneous coronary intervention (PCI). They may also be used to treat acute coronary syndromes (ACS).

©   Mechanism of action of Glycoprotein IIB/IIIA inhibitors:




 

©   Drugs increasing Glycoprotein IIB/IIIA inhibitors associated bleeding include…

Ø Other Antiplatelets (Aspirin, Ticlopidine, Dipyridamole, etc.)

Ø Ginkgo

©   Drug interactions can result in significant morbidity and mortality and thus minimizing the risk for drug interactions should be a goal in drug therapy.

©   The patients on antiplatelet therapy should bring a list of all of the drugs they are taking including prescription drugs, over-the-counter drugs, and any supplements, herbal or otherwise, during their visit to the doctor or pharmacist.

©   The risk of adverse effects could be reduced by healthcare professionals through the screening, education, and follow up on suspected drug interactions.

©   If possible, the patients are recommended to fill all their prescriptions at one pharmacy.

©   Pharmacists can play a crucial role in identifying possible drug interactions by asking patients about their herbal and other alternative medicine product use.


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Drug Interactions of Thiazide Diuretics:

https://www.researchgate.net/publication/342864519_Pharmacodynamic_interactions_of_thiazide_diuretics http://www.ijmdc.com/?mno=51031...